Hi, I think the problem is when the actor is scaled, the edges get blended with the background (it's the default behaviour no matter whether there's an alpha channel or not). Now, because the alpha doesn't have "sharp" edges, some of the white pixels around Guybrush get blended as well, thus resulting in the white graphical artefacts. I see too possible solutions: 1) fill the white space with some dark color (black or dark shadow) or 2) make the alpha channel with sharp edges (i.e. leave the antialiasing to the engine).
Note that all of this only applies to scalable objects.
Well, that's how I see it, maybe some artist will correct me...?